ABSTRACT
Kawasaki disease coronary artery lesions have become one of the common acquired cardiovascular diseases in children in some countries and regions.Giant coronary artery aneurysms are a severe type of Kawasaki disease coronary artery lesion with less likelihood of complete recovery at a later stage, and their cardiovascular event rate and mortality are significantly higher than those of other children with Kawasaki disease.Children with giant coronary aneurysms are at higher risk of cardiovascular disease in adulthood and are closely associated with sudden cardiac death in young adulthood and the development of coronary atherosclerosis in adulthood, with serious implications for the long-term prognosis and quality of life of the child.This article reviews the clinical features and prognosis of Kawasaki disease combined with giant coronary aneurysms.
ABSTRACT
Kawasaki disease is an acute systemic vasculitis of unknown origin. Coronary aneurysm or ectasia is one of the most serious complications of Kawasaki disease. The major complication of Kawasaki coronary disease is myocardial infarction caused by thrombus formation inside the aneurysm or by organic obstructive lesion following the regression of aneurysm. Percutaneous balloon angioplasty, rotational ablation, directional coronary artherectomy, stent insertion and coronary artery bypass graft can be used to treat coronary artery stenosis or occlusion. We describe a 6-year old boy who had an episode of Kawasaki disease with giant coronary artery aneurysm diagnosed at the age of 3 years. Surveillance echocardiogram showed giant coronary aneurysm with stenosis and large mural thrombus in the proximal portion of left main coronary artery. So we inserted two polytetrafluoroethylene(PTFE) covered graft stent without complication.